Nope, don't have to touch the block because of the crank change....
My first exercise was to keep the stock SC rods and use some stock replacement 98+ Mustang 3.8liter pistons...this required taking some of the center counter weights off to clear the piston skirts (cost me 100 bucks to mod the crank) the crank still 0 balanced without Mallory metal so it was a cheap build. and I believe if I had used some forged pistons for that model mustang it would still be running....I cracked a piston due to detonation (I suppose).
I built it to compete in the "fastest stock appearing" class we ran for a couple years and it won...it made 271 hp and 375 torque with a 94/95 blower (unmodded) a stock intercooler and a slightly worked stock MAF, throttlebody and breather box. It did have a little cam in it with some home ported heads. I drove it to work and back daily for nearly a year before the piston cracked so it could have been made to live with minimal changes (meth, or double intercooler, slightly different tune etc.) Dan